Intestinal attraction: CCL25 functions in effector lymphocyte recruitment to the small intestine
                    
                        
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                    چکیده
منابع مشابه
Intestinal attraction: CCL25 functions in effector lymphocyte recruitment to the small intestine.
A large surface area and continuous exposure to the outside environment through food intake make the intestines an ideal location for the growth and/or entry of pathogenic microorganisms and parasites. It is therefore not surprising that large numbers of lymphocytes are associated with the intestines within specialized gut-associated lymphoid tissues (GALT) and in the intestines themselves (1)....
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متن کاملCCL25 mediates the localization of recently activated CD8alphabeta(+) lymphocytes to the small-intestinal mucosa.
The recruitment of antigen-specific T lymphocytes to the intestinal mucosa is central to the development of an effective mucosal immune response, yet the mechanism by which this process occurs remains to be fully defined. Here we show that the CC chemokine receptor 9 (CCR9) is selectively and functionally expressed on murine alpha(E)beta(7)(+) naive CD8alphabeta(+) lymphocytes and a subset of r...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 2002
ISSN: 0021-9738
DOI: 10.1172/jci0216946